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Cancer Weekly

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Salmonellosis Vaccines



Scientists at Peking University, University Health Science Center discuss research in salmonellosis vaccines



June 3rd, 2008

New investigation results, 'Two oral HBx vaccines delivered by live attenuated Salmonella: both eliciting effective anti-tumor immunity,' are detailed in a study published in Cancer Letters. According to a study from Beijing, People's Republic of China, "Live attenuated bacteria have great potential for use in vaccine development due to several unique advantages, including stable antigen expression, effective antigen presentation, convenient and inexpensive delivery, and low cost of vaccine production. In this study, we expressed hepatitis B virus x gene (HBx) on mouse melanoma cells as the target antigen and constructed Salmonella-based HBx vaccines by two strategies, i.e.,...


Source: Cancer Weekly (2008-06-03)

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