Cancer Weekly
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Angiogenesis
Research reports on angiogenesis from University of Marburg provide new insights
June 3rd, 2008
According to a study from Marburg, Germany, "Malignant gliomas are lethal cancers, highly dependent on angiogenesis and treatment options and prognosis still remain poor for patients with recurrent glioblastoma multiforme (GBM). Ephs and ephrins have many well-defined functions during embryonic development of central nervous system such as axon mapping, neural crest cell migration, hindbrain segmentation and synapse formation as well as physiological and abnormal angiogenesis." "Accumulating evidence indicates that Eph and ephrins are frequently overexpressed in different tumor types including GBM. However, their role in tumorigenesis remains controversial, as both...
Source: Cancer Weekly (2008-06-03)
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