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World Journal of Gastroenterology

Can pathological techniques help identify primary colorectal signet ring cell carcinoma?

Published in Cancer Weekly, June 3rd, 2008

Primary colorectal signet ring cell carcinoma is a rare but distinctive malignancy of the large bowel. More than 96% of signet ring cell carcinomas arise in the stomach, with the rest arising from other primary organs. Therefore, a secondary infiltration or metastasis to the colon and rectum must be excluded before a definite diagnosis of primary colorectal signet ring cell carcinoma can be established.

This research, performed by a team led by Professor Hsien Lin Sim, is described in an article to be published on April 7, 2008 in the World Journal of Gastroenterology.

The patient presented with a clinical picture of primary rectal signet ring cell...

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