Oral Squamous Cell Carcinoma

Research from University of Athens has provided new data on oral squamous cell carcinoma

Published in Cancer Weekly, June 3rd, 2008

"Increased levels of interleukin-10 (IL-10) have been observed in patients with oral cancer, possibly as a result of suppression of the immune response. Based on this, the -1082A/G polymorphism, which influences IL-10 gene expression level, was investigated in regard to its possible association with risk for oral cancer," investigators in Athens, Greece report.

"The polymorphism was examined in DNA samples of 144 patients with oral squamous cell carcinoma and 141 healthy controls of equivalent gender, age and ethnicity. The detected allele frequencies for the high expression G allele were significantly higher in patients compared to controls (34.7% versus 21.3%,...

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Source: Cancer Weekly (2008-06-03)

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