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Cancer Weekly

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Astrocytoma



Studies from University of Pavia add new findings in the area of astrocytoma



June 3rd, 2008

"p53 is a cell cycle regulator that has been well-recognized as the key molecule that triggers the induction and the control of cell proliferation and apoptosis in a wide variety of tumours, including astrocytoma. Apoptosis and proliferation are two processes intimately coupled, that occur simultaneously in tumour tissue," scientists in Pavia, Italy report.

"Previous studies of the correlations between proliferation and apoptotic index with p53 expression in astrocytic tumours have remained inconclusive. The aim of this study was to investigate the correlation of p53 expression with the apoptotic index (AI) and the cell proliferation index (PI) in pilocytic astrocytoma...


Source: Cancer Weekly (2008-06-03)

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