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Angiogenesis
Findings from University of Medicine and Dentistry of New Jersey advance knowledge in angiogenesis
June 10th, 2008
A report, 'Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids,' is newly published data in Cardiovascular Research. According to a study from the United States, "Recent evidence suggests that the epoxyeicosatrienoic acids (EETs), which are products of cytochrome P450 (CYP) epoxygenases, possess mitogenic and angiogenic effects in vascular endothelial cells. However, the mechanisms underlying these effects are not fully elucidated." "Because sphingosine kinase (SK) and its product S1P play essential roles in cell growth, survival and migration, we hypothesized that SK activation by...
Source: Cancer Weekly (2008-06-10)
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