Colon Cancer
Research from Shanghai Jiao Tong University in colon cancer provides new insights
Published in Cancer Weekly, June 10th, 2008
In this recent study, researchers in Shanghai, People's Republic of China conducted a study "To investigate the effect and mechanism of blockade of the CXC chemokine receptor-4 (CXCR4) signaling pathway by AMD3100, a small non-peptide CXCR4 inhibitor, on invasion and metastasis of colorectal cancer cells in vitro. Human colorectal cancer cell line SW480 was treated with AMD3100 at different final concentrations. 3-(4,5-dimethylthiazole-2-yl)-2.5-dipheny-Itetrazolium bromide (MTT) assay was used to detect the effect of AMD3100 on cell proliferation."
"The invasion ability of SW480 cells was determined by cell invasion assay kit. In the presence of AMD3100, the...
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Source: Cancer Weekly (2008-06-10)
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