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Cancer Gene Therapy
New cancer gene therapy research from Toho University, Department of Clinical Chemistry outlined
June 10th, 2008
A report, 'Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells,' is newly published data in Glycoconjugate Journal. "The alpha1,3-fucosyltransferase VI (FUT VI) protein is a key enzyme for synthesis of sialyl Lewis X and Lewis X in epithelial cells. Despite its importance, how FUT VI expression is regulated has not previously been elucidated," investigators in Chiba, Japan report. "In this work, we examined transcriptional regulation of the FUT VI gene in hepatocellular carcinoma HepG2 cells. 5'-Rapid amplification of cDNA ends analysis revealed transcription start sites of FUT VI in HepG2 cells at +65 and +278...
Source: Cancer Weekly (2008-06-10)
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