Immunotherapy
Studies from Y. Ohmura and co-authors have provided new information about immunotherapy
Published in Cancer Weekly, June 10th, 2008
According to recent research from Japan, "One new approach to cancer therapy is based on the adoptive transfer of tumor-specific cytotoxic T cells and anti-CD25 antibodies. In the present study, CD8(+) and IFN-gamma secreting T lymphocytes (CTLs) were enriched as tumor-specific cytotoxic T cells from spleen lymphocytes of mice bearing the Renca tumor (a murine renal carcinoma line originating from a BALB/c mouse) after stimulation with tumor cells."
"An anti-CD25 IL-2R alpha(anti-CD25) mAb from hybridoma PC61 was used for depletion for CD4(+)CD25(+) regulatory T (Treg) cells. Treatment-efficacy for tumor-bearing mice was compared using 4 systems: 1, whole spleen...
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Source: Cancer Weekly (2008-06-10)
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