Large-Cell Lymphoma
Report summarizes large-cell lymphoma study findings from F.M. Fadlelmola and co-researchers
Published in Cancer Weekly, June 10th, 2008
According to recent research from Vancouver, Canada, "Hodgkin lymphoma (HL) and Anaplastic Large Cell Lymphoma (ALCL), are forms of malignant lymphoma defined by unique morphologic, immunophenotypic, genotypic, and clinical characteristics, but both overexpress CD30. We used sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization to screen HL-derived cell lines (KMH2 and L428) and ALCL cell lines (DEL and SR-786) in order to identify disease-associated gene copy number gains and losses."
"Significant copy number gains and losses were observed on several chromosomes in all four cell lines. Assessment of copy number alterations with 26,819 DNA...
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Source: Cancer Weekly (2008-06-10)
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