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Cancer Weekly

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Adenocarcinoma



Studies from Okayama University provide new data on adenocarcinoma



June 10th, 2008

According to recent research from Okayama, Japan, "We investigated EGFR and KRAS alterations among atypical adenomatous hyperplasia and small lung adenocarcinomas with bronchioloalveolar features to understand their role during multistage pathogenesis. Sixty lesions measuring 2 cm or less were studied, including 38 noninvasive lesions (4 atypical adenomatous hyperplasias, 19 Noguchi type A and 15 type B) and 22 invasive lesions (type Q based on the World Health Organization classification and Noguchi's criteria."

"EGFR and KRAS mutations were examined using PCR-based assays. EGFR copy number was evaluated using fluorescence in situ hybridization. EGFR and KRAS mutations...


Source: Cancer Weekly (2008-06-10)

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