Cancer Weekly
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Adenoid Cystic Cancer
Reports from University of Pennsylvania describe recent advances in adenoid cystic cancer
June 10th, 2008
According to a study from the United States, "CD43, a sialoglycoprotein expressed on hematopoietic cells, has only rarely been reported in nonhematopoietic tumors, mostly of colon. We describe CD43 expression by immunohistochemistry and mRNA in situ hybridization in adenoid cystic carcinomas (ACCs)." "CD43 immunoreactivity with 2 different antibodies was detected mainly in ACC but also 1 membranous type basal cell adenocarcinoma and 1 colonic adenocarcinoma. Nine of 20 (45%) ACC (8/17 salivary/mucoserous and 1/3 mammary) showed immunoreactivity with clone MT1 whereas 4 (23.5%) salivary ACC also showed immunoreactivity with clone DF-T1. The few high-grade, angioinvasive...
Source: Cancer Weekly (2008-06-10)
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