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Adenoid Cystic Cancer
Scientists at University of Sao Paulo publish research in adenoid cystic cancer
June 10th, 2008
"Adenoid cystic carcinoma is a frequent malignant salivary gland neoplasm with high levels of recurrence and metastasis. This neoplasm expresses prominent extracellular matrix (ECM)," scientists writing in the International Journal of Experimental Pathology report. "We are studying regulatory mechanisms underlying secretion of ECM molecules in adenoid cystic carcinoma. We have previously demonstrated that laminin modulates the phenotype of a human adenoid cystic carcinoma (CAC2) cell line. Thus, this molecule would be a good candidate to regulate secretion of ECM molecules in these cells. Here we analysed the role played by laminin-111 [formerly laminin-1;...
Source: Cancer Weekly (2008-06-10)
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