Necrosis
Recent studies from Pusan National University add new data to necrosis
Published in Cancer Weekly, June 10th, 2008
According to a study from South Korea, "Sodium salicylate, the active metabolite of aspirin, has been shown to exert anti-inflammatory activities by inhibiting the expression of various pro-inflammatory factors, and has potent anti-cancer effects against a number of human cancers including colon, lung, breast and leukemia. Necrotic cell death is emerging as one of the crucial factors that trigger an inflammatory response since during necrotic death the cell membrane is ruptured and the intracellular constituents including high mobility group box 1 (HMGB1) are released into the extracellular space, thereby activating an inflammatory response."
"In contrast, autophagic...
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Source: Cancer Weekly (2008-06-10)
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