Urothelial Cancer

Reports on urothelial cancer findings from Kaohsiung Medical University provide new insights

Published in Cancer Weekly, June 10th, 2008

According to recent research from Kaohsiung, Taiwan, "Hypoxia inducible factor (HIF)-1 alpha is a critical regulatory protein of cellular response to hypoxia and is closely related to angiogenic process. To explore the potential role and the prognostic value of HIF-1 alpha in urothelial carcinoma (UC)."

"Clinicopathological and follow-up data on 99 UC cases were reviewed and immunostained for HIF-1 alpha, CD68, vascular endothelial growth factor (VEGF) and CD34 antigen. Tumour-associated macrophage (TAM) counts and HIF-1 alpha expression were compared with clinicopathologic characteristics, overall survival (OS) and disease-free survival rates (DFS). High expression of...

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Source: Cancer Weekly (2008-06-10)

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