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Cancer Weekly

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Apoptosis



New apoptosis findings from University of Leipzig published



June 10th, 2008

According to recent research published in the journal Methods and Findings in Experimental and Clinical Pharmacology, "Our aim was to investigate the photophysical and photodynamic properties of anew, water-soluble positively charged and chemicaly stable photosensitizer: tetrahydroporphyrin tetratosylat (THPTS). Absorption, fluorescence and H-1 NMR spectra and the intracellular distribution of THPTS were measured."

"The apoptosis in choroidal melanoma cells was measured using cell death detection ELISA and caspase-8 activity assay. THPTS-PDT efficiency was studied in Balb/c mice bearing C26 colon carcinoma. Subcutaneously located tumors were irradiated with a...


Source: Cancer Weekly (2008-06-10)

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