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Cancer Weekly

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Apoptosis



Reports outline apoptosis study findings from Nagoya City University, Medical Department



June 10th, 2008

Researchers in Nagoya, Japan conducted a study "To evaluate proliferation and apoptosis in high-grade sarcomas of the extremities before and after preoperative radio-hyperthermo-chemotherapy (RHC) and to determine the relationship between these parameters and treatment outcomes. Pre- and post-RHC specimens of 41 soft tissue and bone tumours were immunohistochemically stained for minichromosome maintenance protein (MCM) 2 and caspase 3 as proliferation and apoptosis markers, respectively, based on a preliminary study comparing them with conventional markers."

"Indices were calculated as a percentage of positive cells by counting tumour cells in the most frequently...


Source: Cancer Weekly (2008-06-10)

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