Cancer Weekly
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B-Cell Lymphoma
Studies from Columbia University in the area of B-cell lymphoma published
June 10th, 2008
According to recent research from the United States, "The computational identification of oncogenic lesions is still a key open problem in cancer biology. Although several methods have been proposed, they fail to model how such events are mediated by the network of molecular interactions in the cell." "In this paper, we introduce a systems biology approach, based on the analysis of molecular interactions that become dysregulated in specific tumor phenotypes. Such a strategy provides important insights into tumorigenesis, effectively extending and complementing existing methods. Furthermore, we show that the same approach is highly effective in identifying the targets of...
Source: Cancer Weekly (2008-06-10)
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