Life Sciences
Reports outline life sciences study findings from University of Illinois
Published in Cancer Weekly, June 10th, 2008
Investigators publish new data in the report 'A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells.' "Estrogen receptor alpha (ERalpha) plays an important role in several human cancers. Most current ERalpha antagonists bind in the receptor ligand binding pocket and compete for binding with estrogenic ligands," scientists in the United States report.
"Instead of the traditional approach of targeting estrogen binding to ER, we describe a strategy using a high throughput fluorescence anisotropy microplate assay to identify small molecule inhibitors of ERalpha binding to consensus...
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Source: Cancer Weekly (2008-06-10)
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