Brain Cancer
New brain cancer study findings have been published by scientists at University of California
Published in Cancer Weekly, June 10th, 2008
"Glioblastoma multiforme (GBM) is an invasive and aggressive primary brain tumor which is associated with a dismal prognosis. We have earlier developed a macroscopic, intracranial, syngeneic GBM model, in which treatment with adenoviral vectors (Ads) expressing herpes simplex virus type 1 thymidine kinase (HSV1-TK) plus ganciclovir (GCV) resulted in survival of similar to 20% of the animals," scientists in the United States report.
"In this model, treatment with Ads expressing Fms-like tyrosine kinase 3 ligand (FIt3L), in combination with Ad-HSV1-TK improves the survival rate to similar to 70% and induces systemic antitumor immunity. We hypothesized that the growth of a...
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Source: Cancer Weekly (2008-06-10)
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