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Life Sciences
Recent studies from Wayne State University add new data to life sciences
June 17th, 2008
A report, 'Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage,' is newly published data in Experimental Cell Research. According to recent research from the United States, "We have shown that overexpression of SMS1, an enzyme that converts de novo ceramide into sphingomyelin, is accompanied by attenuated ceramide response and apoptotic resistance after photodamage with the photosensitizer Pc 4 (photodynamic therapy; PDT). To test whether SMS1 overexpression-related effects after PDT can be reversed, in this study SMS1 was downregulated in Jurkat T lymphoma/leukemia cells using small...
Source: Cancer Weekly (2008-06-17)
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