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Cancer Weekly

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Angiogenesis



Researchers from Medical University of Graz provide details of new studies and findings in the area of angiogenesis



June 17th, 2008

According to recent research from Graz, Austria, " Tumor growth requires the formation of new blood vessels, a phenomenon known as angiogenesis. The most important regulator of angiogenesis is vascular endothelial growth factor (VEGF)."

"Several common polymorphisms in the VEGF-gene have been associated with different VEGF expression, production and plasma levels according to allele status, and influence the risk of developing different types of cancer. Therefore, these variants might be risk factors for colorectal cancer (CRC). In the present case-control study, VEGF genotypes of the +936 C> T, -2578 C> A and -634 G> C polymorphisms were determined in 427...


Source: Cancer Weekly (2008-06-17)

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