Cancer Weekly
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Basal Cell Cancer
Studies from Boston University, Medical Department in the area of basal cell cancer published
June 17th, 2008
According to a study from the United States, "Treatment with thymidine dinucleotide (pTT) has well documented DNA-protective effects and reduces development of squamous cell carcinoma in UV-irradiated mice. The preventive effect of pTT on basal cell carcinoma (BCC) was evaluated in UV-irradiatedPtcb-1(+/-) mice, a model of the human disease Gorlin syndrome." "Topical pTT treatment significantly reduced the number and size (P < 0.001) of BCCs in murine skin after 7 months of chronic irradiation. Skin biopsies collected 24 hours after the final UV exposure showed that pTT reduced the number of nuclei positive for cyclobutane pyrimidine dimers by 40% (P < 0.0002) and...
Source: Cancer Weekly (2008-06-17)
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