Cancer Weekly
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RNA Research
Studies from Fourth Military Medical University in the area of RNA research described
June 24th, 2008
"Livin, a novel member of the human inhibitors of apoptosis protein ( IAP) family, plays an important role in tumor progression and occurrence by inhibiting cell apoptosis. It is selectively expressed in the most common human neoplasms and appears to be involved in tumor cell resistance to chemotherapeutic agents," scientists in Xian, People's Republic of China report. "To investigate its possibility as a therapeutic target for human malignancies, we established two genetically different stable tumor cell lines ( LoVo and SPCA-1) and RNA interference ( RNAi) technique was employed to downregulate Livin expression in two human tumor cell lines. The specific...
Source: Cancer Weekly (2008-06-24)
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