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Cancer Gene Therapy
Data on cancer gene therapy published by researchers at Tongji Hospital, Tongji Medical College
June 24th, 2008
Data detailed in 'Targeting gene therapy for hepatocarcinoma cells with the E. coli purine nucleoside phosphorylase suicide gene system directed by a chimeric alpha-fetoprotein promoter' have been presented. According to recent research published in the journal Cancer Letters, "For hepatocarcinoma (HCC) gene therapy, the tumoricidal efficacy and selective expression of therapeutic gene remain two major challenges. The Escherichia coli (E. coli) purine nucleoside phosphorylase (PNP)/9-(2-deoxy-beta-dribofuranosyl)-6-methylpurine (MeP-dR) suicide gene system exhibits excellent anti-tumor effects, indicating this system directed by a HCC-specific promoter would offer a...
Source: Cancer Weekly (2008-06-24)
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