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Cancer Weekly

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Cancer Gene Therapy



Researchers at University of Toyama have published new data on cancer gene therapy



June 24th, 2008

A new study, 'Construction of X-ray-inducible promoters through cis-acting element elongation and error-prone polymerase chain reaction,' is now available. "A promoter that is activated by ionizing radiation may be a useful tool for cancer therapy since, with such a promoter, the therapeutic gene can be expressed only in cancer tissues by irradiation. An artificially constructed promoter is advantageous as natural promoters may have physiological limitations," investigators in Toyama, Japan report.

"However, reasonably designing a promoter is hampered by shortage of information about the relationship between the structure and properties of a promoter DNA. Binding sites...


Source: Cancer Weekly (2008-06-24)

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