Gastric Cancer
Shimane University, Medical Department reports research in gastric cancer
Published in Cancer Weekly, June 24th, 2008
According to a study from Izumo, Japan, "Fractalkine (CX3CL1) is the only CX3C chemokine that can chemoattract natural killer (NK) cells, CD8(+) T cells, monocytes, and dendritic cells. Although experimental studies have demonstrated that Fractalkine expression by tumor cells is related to the infiltrating lymphocytes and initiates antitumor immunity, the clinical significance of Fractalkine remains to be elucidated in gastric adenocarcinoma."
"Tissue sections from 158 patients with curatively resected T2 or T3 gastric adenocarcinoma were immunohistochemically stained for Fractalkine. Furthermore, to evaluate CD8(+) T cells and NK cells infiltration, antibodies to CD8...
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Source: Cancer Weekly (2008-06-24)
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