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Cancer Weekly

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Cancer Gene Therapy



Researchers from Technical University of Dresden, Department of Urology publish findings in cancer gene therapy



June 24th, 2008

Scientists discuss in 'Antisense-mediated inhibition of survivin, hTERT and VEGF in bladder cancer cells in vitro and in vivo' new findings in cancer gene therapy. According to recent research from Dresden, Germany, "Since cancer cells are characterised by multiple genetic alterations the single inhibition of one tumour-associated gene might not be sufficient as a therapeutic strategy. We examined the effects of a combined inhibition of survivin, human telomerase reverse transcriptase (hTERT) and vascular endothelial growth factor (VEGF) with antisense oligodeoxynucleotides (AS-ODNs) and small interfering RNAs (siRNAs) in EJ28 and 5637 bladder cancer (BCa) cells."

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Source: Cancer Weekly (2008-06-24)

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