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Myeloma Gene Therapy
Reports from Institute for Cancer Research advance knowledge in myeloma gene therapy
June 24th, 2008
New investigation results, 'Streptolysin-O reversible permeabilisation is an effective method to transfect siRNAs into myeloma cells,' are detailed in a study published in Journal of Immunological Methods. "RNA interference (RNAi) has been shown to be a valuable tool to specifically target gene expression in a number of organisms becoming an indispensable weapon in the arsenal in functional genomics. In this study, we demonstrate that streptolysin-O (SLO) reversible permeabilisation is an efficient method to deliver small interfering RNAs (siRNAs) to hard-to-transfect human myeloma cell lines," researchers in London, the United Kingdom report. "We used published,...
Source: Cancer Weekly (2008-06-24)
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