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Cancer Weekly

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Angiogenesis



Studies from R. Hasina and co-authors have provided new information about angiogenesis



June 24th, 2008

"The literature contains numerous references describing heterogeneity for tumor phenotypes including cell proliferation, invasiveness, metastatic potential, and response to therapies. However, data regarding angiogenic heterogeneity are limited," scientists writing in the journal Laboratory Investigation report.

"In this study, we investigated the degree of intertumoral angiogenic heterogeneity present in head and neck squamous cell carcinomas (HNSCC). In addition, we investigated the biological relevance that this heterogeneity may have in the context of cytokine directed antiangiogenic therapy. Keratinocytes were harvested from HNSCC specimens using laser...


Source: Cancer Weekly (2008-06-24)

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