Cancer Gene Therapy
Reports summarize cancer gene therapy research from University of Michigan, Medical Department
Published in Cancer Weekly, June 24th, 2008
"In this report, we developed a chimeric receptor ( N29 gamma chR) involving the single chain Fv ( scFv) derived from N29 monoclonal antibody ( mAb) specific for p185HER2 and characterized the therapeutic efficacy of primary T cells engineered to express N29g chR in two histologically distinct murine tumor models. Murine breast ( MT901) and fibrosarcoma ( MCA207) cancer cell lines were engineered to express human HER2 as targets," scientists in the United States report.
"Administration of N29 gamma chR-expressing T cells eliminated 3-day pulmonary micrometastases of MT901/ HER2 and MCA207/ HER2 but not parental tumor cells. A 5 to 8-fold increased dose of N29g T cells...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2008-06-24)
More Articles from Cancer Weekly
- Cure Lab, Inc.
A protein sequence associated with Huntington's disease may become life-saving vaccine component - Research
Outing the outliers: Strategy matches oncogene with subtype of prostate cancer - Cancer Gene Therapy
Reports outline cancer gene therapy research from Kaohsiung Medical University - Cancer Gene Therapy
Scientists at Wuhan University describe research in cancer gene therapy - Cancer Gene Therapy
Study results from National Cancer Institute in the area of cancer gene therapy published - Cancer Gene Therapy
Study results from University of Miami in the area of cancer gene therapy published - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
