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Cancer Gene Therapy
Study results from National Cancer Institute in the area of cancer gene therapy published
June 24th, 2008
According to recent research published in the journal Cancer Gene Therapy, "Our recent study showing highly recurrent loss of function of DLC1 ( deleted in liver cancer 1), a tumor suppressor gene in primary prostate carcinoma ( PCA), implicates this gene in the pathogenesis of this disease. To evaluate the response of PCA to oncosuppressive activity of DLC1, we examined now the effects of adenoviral vector for human DLC1 transduction into the DLC1-deficient, androgen-independent ( AI) and aggressive human PCA cell lines PC-3 and C4-2-B2." "Adenovirus-mediated restoration of DLC1 expression inhibited the proliferation, invasiveness and anchorage-independent...
Source: Cancer Weekly (2008-06-24)
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