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Cancer Gene Therapy
Research results from Peking University, Beijing National Laboratory for Molecular Sciences update knowledge of cancer gene therapy
July 1st, 2008
Research findings, 'Reduction of Akt2 expression inhibits chemotaxis signal transduction in human breast cancer cells,' are discussed in a new report. According to recent research from Beijing, People's Republic of China, "Protein kinase Czeta PKCzeta mediates cancer cell chemotaxis by regulating cytoskeleton rearrangement and cell adhesion. In the research for its upstream regulator, we investigated the role of Akt2 in chemotaxis and metastasis of human breast cancer cells." "Reduction of Akt2 expression by siRNA inhibited chemotaxis of MDA-MB-231, T47D, and MCF7 cells, three representative human breast cancer cells. Expression of a wild type Akt2 in siRNA transfected...
Source: Cancer Weekly (2008-07-01)
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