Carcinosarcoma

New carcinosarcoma study findings have been reported from A. Schipf et al

Published in Cancer Weekly, July 1st, 2008

According to a study from Luzern, Switzerland, "The origin of carcinosarcomas of the ovary and uterus has long been discussed. In this study, we used a molecular-genetic approach to elucidate the tumorigenesis of carcinosarcomas of these organs correlating our findings with the specific biphasic pattern of these tumors."

"We analyzed a series of 30 paraffin-embedded carcinosarcomas of the ovary and the uterus using comparative genomic hybridization (CGH) and fluorescence in-situ hybridization (FISH). In general, gains (85%) were observed more frequently, than losses (30%). Characteristic and frequent chromosomal amplification was observed on chromosome 8q and 20q (42...

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Source: Cancer Weekly (2008-07-01)

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