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Cancer Weekly

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Life Sciences



Researchers at University College, Institute of Child Health target life sciences



July 1st, 2008

Investigators publish new data in the report 'Investigation of endogenous antigen processing by delivery of an intact protein into cells.' "Investigation of MHC class I endogenous antigen processing and presentation is important for understanding non-self immune recognition, vaccine design, immune evasion by pathogens and tumours, and elucidation of the mechanisms of certain auto-immune diseases. To study the MHC class I antigen-processing pathway, the protein antigen of interest has to be expressed inside the cells," scientists in London, the United Kingdom report.

"To express a desired protein antigen, delivery of protein coding genes into the cell using transfection...


Source: Cancer Weekly (2008-07-01)

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