Published in Cancer Weekly, July 1st, 2008
"After 48 It of incubation, jaspolide B inhibited the growth of Bel-7402 and HepG2 cells with IC50 values of 29.1 and 29.5 mc M, respectively. Incubation with 0.5 mc M of jaspolide B caused time-dependent induction of apoptosis in up to 66.8% of Bel-7402 cells for 48 h, and the induction of apoptosis was confirmed by the enhancement of mitochondrial masses and cell membrane permeability, and nuclear condensation in Bel-7402 and HepG2 cells. Moreover,...
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