Laryngeal Cancer

New findings from Pomeranian Medical University in the area of laryngeal cancer published

Published in Cancer Weekly, July 1st, 2008

"Mutations in the CHEK2 gene have been associated with increased risks of breast, prostate and colon cancer. In contrast, a previous report suggests that individuals with the I157T missense variant of the CHEK2 gene might be at decreased risk of lung cancer and upper aero-digestive cancers," scientists in Szczecin, Poland report.

"To confirm this hypothesis, we genotyped 895 cases of lung cancer, 430 cases of laryngeal cancer and 6391 controls from Poland for four founder alleles in the CHEK2 gene, each of which has been associated with an increased risk of cancer at several sites. The presence of a CHEK2 mutation was protective against both lung cancer [odds ratio (OR)...

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Source: Cancer Weekly (2008-07-01)

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