Cancer Weekly
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Angiogenesis
Research from Y. Mori and co-researchers in the area of angiogenesis described
July 1st, 2008
According to recent research published in the journal Cancer Science, "We previously reported that 3'-sulfoquinovosyl-1'-monoacylglycerol (SQMG) was effective in suppressing the growth of solid tumors due to hemorrhagic necrosis in vivo. In the present study, we investigated the antiangiogenic effect of SQMG." "In vivo assessment of antitumor assays showed that some tumor cell lines, but not others, were sensitive to SQMG. Microscopic study suggested that in SQMG-sensitive tumors, but not SQMG-resistant tumors, angiogenesis was reduced. We next investigated gene expression relating to angiogenesis in tumor tissues by quantitative real-time polymerase chain...
Source: Cancer Weekly (2008-07-01)
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