Prostate-Specific Antigen

Scientists at GlaxoSmithKline describe research in prostate-specific antigen

Published in Cancer Weekly, July 1st, 2008

According to recent research published in the Journal of Urology, "Dutasteride and finasteride are 5 alpha-reductase inhibitors that dramatically decrease serum levels of dihydrotestosterone. Because androgens affect bone, lipids, hematopoiesis, prostate and sexual function, we determined the impact of 5 alpha-reductase inhibitors on these end points."

"We conducted a randomized, double-blinded, placebo controlled trial of 99 men 18 to 55 years old randomly assigned to receive 0.5 mg dutasteride (33), 5 mg finasteride (34) or placebo (32) daily for 1 year. Bone mineral density was measured at baseline, after 1 year of treatment and 6 months after drug...

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Source: Cancer Weekly (2008-07-01)

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