Trophoblastic Neoplasms

Data from University of Louvain provide new insights into trophoblastic neoplasms

Published in Cancer Weekly, July 1st, 2008

"We report a case of ovarian malignant intermediate-type trophoblastic tumor in a clinically normal, nonpregnant 4-year-old rhesus monkey (Macaca mulatta). A large solid lobulated mass replaced the right ovary and filled the pelvis," scientists writing in the journal Veterinary Pathology report.

"Multiple metastases were observed within the lungs and the liver. The tumor was histologically identified as predominantly composed of intermediate trophoblastic cells, without prominent hemorrhages and the classic bilaminar pattern of cyto- and syncytiotrophoblastic cells characteristic of choriocarcinoma. Immunohistochemical analysis showed the presence of placental...

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Source: Cancer Weekly (2008-07-01)

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