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Cancer Therapy

New research on cancer therapy from J. de Graeve and co-authors summarized

Published in Cancer Weekly, July 1st, 2008

Fresh data on cancer are presented in the report 'Metabolism pathway of vinorelbine (Navelbine) in human: characterisation of the metabolites by HPLC-MS/MS.' According to recent research from Sart Tilman, Belgium, "The biotransformation of vinorelbine (VRL), an anti-neoplastic vinca-alkaloid derivate already marketed for nonsmall cell lung cancer and advanced breast cancer as an i.v. form and currently registered in several countries as an oral form, was investigated in human. Biological specimen from several human sources constituted the material for the metabolic identification in human."

"An isocratic liquid chromatographic system composed of 40 mM ammonium acetate...

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