Epilepsy
Research from Institute of Neurosciences yields new findings on epilepsy
Published in Cancer Weekly, July 1st, 2008
Research findings, 'Analysis of LGI1 promoter sequence, PDYN and GABBR1 polymorphisms in sporadic and familial lateral temporal lobe epilepsy,' are discussed in a new report. "Autosomal dominant lateral temporal epilepsy (ADTLE) is a genetically transmitted epileptic syndrome characterized by focal seizures with predominant auditory symptoms likely originating from the lateral region of the temporal lobe. Mutations in coding region or exon splice sites of the leucine-rich, glioma-inactivated 1 (LGI1) gene account for about 50% of ADLTE families," scientists in Padova, Italy report.
"De novo LGI1 mutations of the same kind have also been found in about 2.5% of...
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Source: Cancer Weekly (2008-07-01)
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