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Gene Therapy

New gene therapy research from Beijing Institute of Radiation Medicine discussed

Published in Cancer Weekly, July 1st, 2008

Fresh data on gene therapy are presented in the report 'Ceap/BLOS2 interacts with BRD7 and selectively inhibits its transcription-suppressing effect on cellular proliferation-associated genes.' According to a study from Beijing, People's Republic of China, "The centrosome associated protein Ceap-16 (also termed BLOS2) can accelerate the proliferation of mouse fibroblast NIH3T3 cells, which mechanism remains unclear. Here we identified tumor suppressor candidate BRD7 (bromodomain containing protein 7), which could negatively regulate cell proliferation and growth, as a novel Ceap-16-interacting protein."

"Ceap-16 and BRD7 interacted with each other both in vitro and in...

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