Sarcoma
Studies from Medical College of Wisconsin provide new data on sarcoma
Published in Cancer Weekly, July 1st, 2008
Fresh data on sarcoma are presented in the report 'Characterization of Rous sarcoma virus polyadenylation site use in vitro.' "Polyadenylation of Rous sarcoma virus (RSV) RNA is inefficient, as approximately 15% of RSV RNAs represent read-through transcripts that use a downstream cellular polyadenylation site (poly(A) site). Read-through transcription has implications for the virus and the host since it is associated with oncogene capture and tumor induction," scientists in the United States report.
"To explore the basis of inefficient RSV RNA 3'-end formation, we characterized RSV polyadenylation in vitro using HeLa cell nuclear extracts and HEK293 whole cell extracts....
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Source: Cancer Weekly (2008-07-01)
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