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HIV/AIDS Gene Therapy
Study results from University of Washington, Department of Microbiology provide new insights into HIV/AIDS gene therapy
July 8th, 2008
Scientists discuss in 'RNase H activity: structure, specificity, and function in reverse transcription' new findings in HIV/AIDS. "This review compares the well-studied RNase H activities of human immunodeficiency virus, type 1 (HIV-1) and Moloney murine leukemia virus (MoMLV) reverse transcriptases. The RNase H domains of HIV-1 and MoMLV are structurally very similar, with functions assigned to conserved subregions like the RNase H primer grip and the connection subdomain, as well as to distinct features like the C-helix and loop in MoMLV RNase H," scientists writing in the journal Virus Research report. "Like cellular RNases H, catalysis by the retroviral...
Source: Cancer Weekly (2008-07-08)
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