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Immunization
Scientists at University catholique of Louvain, Ludwig Institute for Cancer Research describe research in immunization
July 8th, 2008
Research findings, 'Vaccination of a melanoma patient with mature dendritic cells pulsed with MAGE-3 peptides triggers the activity of nonvaccine anti-tumor cells,' are discussed in a new report. "We previously characterized the CTL response of a melanoma patient who experienced tumor regression following vaccination with an ALVAC virus coding for a MAGE-A3 Ag. Whereas anti-vaccine CTL were rare in the blood and inside metastases of this patient, anti-tumor CTL recognizing other tumor Ags, mainly MAGE-C2, were 100 times more frequent in the blood and considerably enriched in metastases following vaccination," investigators in Brussels, Belgium report. "In this study we...
Source: Cancer Weekly (2008-07-08)
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