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Cancer Weekly

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Smallpox Gene Therapy



New smallpox gene therapy study findings reported from S. Vigne and co-authors



July 8th, 2008

Scientists discuss in 'Specific inhibition of orthopoxvirus replication by a small interfering RNA targeting the D5R gene' new findings in smallpox. According to recent research from Grenoble, France, "Concerns about the potential use of smallpox in bioterrorism have stimulated interest in the development of novel antiviral treatments. Currently, there are no effective therapies against smallpox and new treatment strategies are greatly needed."

"In this study, specifically designed small interfering RNAs (siRNAs), targeting five proteins essential for orthopoxvirus replication, were investigated for their ability to inhibit vaccinia virus strain Western Reserve (VACVWR)...


Source: Cancer Weekly (2008-07-08)

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