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Cancer Gene Therapy
Study data from Xi'an Jiao Tong University, Medical Department provide new insights into cancer gene therapy
July 8th, 2008
According to a study from Xian, People's Republic of China, "The novel human oncogene hWAPL is associated with uterine cervical cancer. The HPV16 E5 oncoprotein could induce genomic instability in normal human cells." "However, the mechanism of E5 interaction with hWAPL still awaits definition. In our present studies, the eukaryotic expression plasmids, pcDNA3-hWAPL and pcDNA3-hWAPL-E5 were constructed and carried out to vaccinate mice directly. The result that indicated the polyclonal antibody titer in immunized mice sera was increased by enzyme-linked immunosorbent assay. In addition, the proliferative responses of immunized mice spleen cells showed the optical...
Source: Cancer Weekly (2008-07-08)
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