Cancer Weekly
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Angiogenesis
Investigators at Kobe University zero in on angiogenesis
July 8th, 2008
According to recent research published in the journal Hepato - Gastroenterology, "Bckground/Aims: TNP-470, an angiogenesis inhibitor, has already been used in combination with chemotherapy to enhance its antitumor activity. The mechanism of enhanced antitumor activity in combination therapy has not been clarified, however, and few studies have described the combined effect of TNP-470 and 5-fluorouracil (5-FU) on gastric cancer." "The present study was conducted to investigate the effect of TNP-470 + 5-FU on gastric cancer cell line MKN-45 in vivo and in vitro. MKN-45 cells were subcutaneously injected into mice that were divided into 4 groups: a control group, a...
Source: Cancer Weekly (2008-07-08)
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