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Cancer Gene Therapy
National Taiwan University, Department of Primary Care describes research in cancer gene therapy
July 15th, 2008
Fresh data on cancer gene therapy are presented in the report 'Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion.' According to recent research from Taipei, Taiwan, "Cysteine-rich 61 (Cyr61/CCN1), one of the members of CCN family, has been implicated in the progression of human malignancies. Previously, our studies have demonstrated that Cyr61/CCN1 has a role in promoting gastric cancer cell invasion, but the mechanism is not clear yet." "Here, we found that hypoxia-inducing factor-1alpha (HIF-1alpha) protein, but not mRNA, expression was significantly elevated in...
Source: Cancer Weekly (2008-07-15)
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